BDBM50354138 CHEMBL1836215

SMILES CC(C)Oc1ccc(cc1C#N)-c1nc(no1)-c1ccc2CN(CCc2c1C)C(CO)CO

InChI Key InChIKey=GOJFPSNMWCYOTJ-UHFFFAOYSA-N

Data  6 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50354138   

TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of CYP3A4 using vivid red as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP3A4 using vivid green as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataEC50:  3.16nMAssay Description:Agonist activity at human S1P1 receptor expressed in CHO-K1 EDG1 cells expressing beta-arrestin 2 after 105 mins by chemi-luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataEC50: >3.16E+4nMAssay Description:Agonist activity at human S1P3 receptor expressed in RBL cells assessed as [35S]GTPgammaS binding after 3 hrs by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50354138(CHEMBL1836215)
Affinity DataEC50:  19.9nMAssay Description:Agonist activity at human S1P5 receptor expressed in CHO-K1 aequorin cells assessed as calcium accumulation of by luminescence assay in presence of c...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed