BDBM50353844 CHEMBL270341::US9604926, Compound CM-145::US9724435, Compound CM-145

SMILES O=c1sc2ccccc2n1CCCCN1CCN(CC1)C1CCCCC1

InChI Key InChIKey=ZACKDLLCPUTVQK-UHFFFAOYSA-N

Data  10 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50353844   

TargetSigma intracellular receptor 2(Rat)
The University of Mississippi

US Patent
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  0.390nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Rat)
The University of Mississippi

US Patent
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  0.390nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Mouse)
The University of Mississippi

US Patent
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  0.390nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSigma intracellular receptor 2(Mouse)
The University of Mississippi

US Patent
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  0.390nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  4.17nMAssay Description:Displacement of (-)-[3H]pentazocine from sigma 1 receptor in rat brain membrane after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  4.17nMAssay Description:Displacement of [3H](+)-pentazocine from opioid sigma1 receptor in rat brain homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Rat)
The University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Mouse)
The University of Mississippi

US Patent
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSigma non-opioid intracellular receptor 1(Mouse)
The University of Mississippi

US Patent
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent