BDBM50353587 CHEMBL12543

SMILES CN1CCCC1=O

InChI Key InChIKey=SECXISVLQFMRJM-UHFFFAOYSA-N

Data  5 IC50

PDB links: 12 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50353587   

TargetBromodomain adjacent to zinc finger domain protein 2B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50353587(CHEMBL12543)
Affinity DataIC50: 3.40E+7nMAssay Description:Inhibition of BAZ2BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50353587(CHEMBL12543)
Affinity DataIC50: 2.30E+6nMAssay Description:Inhibition of CREBBPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50353587(CHEMBL12543)
Affinity DataIC50: 2.66E+6nMAssay Description:Inhibition of GST-tagged BRD4 BD1 (49 to 170 residues) (unknown origin) using streptavidin-D2 biotinylated tetra-acetylated histone H4 peptide as sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetBromodomain-containing protein 2(Human)
University of S£O Paulo

Curated by ChEMBL
LigandPNGBDBM50353587(CHEMBL12543)
Affinity DataIC50: 9.00E+6nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) using biotin-H4Ac4 as substrate preincubated for 30 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50353587(CHEMBL12543)
Affinity DataIC50: 6.00E+6nMAssay Description:Inhibition of BRD4 BD1 (unknown origin) using biotin-H4Ac4 as substrate preincubated for 30 mins followed by substrate addition and measured after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed