BDBM50352683 CHEMBL1823097

SMILES Cc1nc(C(=O)NCCCN2CCN(CC2)c2cccc(C)c2C)c(C)n1-c1ccc2OCCOc2c1

InChI Key InChIKey=PXEUWAFHVKNLLD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50352683   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352683(CHEMBL1823097)
Affinity DataIC50: 40.6nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352683(CHEMBL1823097)
Affinity DataIC50: 4.00E+3nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352683(CHEMBL1823097)
Affinity DataIC50: 6.08nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50352683(CHEMBL1823097)
Affinity DataIC50: 8.70E+3nMAssay Description:Displacement of [3H]astemizole from human ERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352683(CHEMBL1823097)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 by luceferin-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352683(CHEMBL1823097)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human recombinant CYP2C9 by luceferin-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352683(CHEMBL1823097)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of human recombinant CYP2D6 by luceferin-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352683(CHEMBL1823097)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 by luceferin-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed