BDBM50352661 CHEMBL1823075::US8835436, Example 122

SMILES CCCc1nc(C(=O)NCCCN2CCN(CC2)c2cccc(C)c2C)c(C)n1-c1ccc(OC)cc1

InChI Key InChIKey=DXQCCZNEUHNYEV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50352661   

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandPNGBDBM50352661(CHEMBL1823075 | US8835436, Example 122)
Affinity DataIC50: 70.8nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandPNGBDBM50352661(CHEMBL1823075 | US8835436, Example 122)
Affinity DataIC50: 130nMpH: 7.4Assay Description:For serotonin 5-HT2A binding, an aliquot of human recombinant serotonin 5-HT2A receptor (PerkinElmer Life and Analytical Sciences, USA) expressed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2015
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Green Cross

US Patent
LigandPNGBDBM50352661(CHEMBL1823075 | US8835436, Example 122)
Affinity DataIC50: 70.8nMAssay Description:Displacement of [3H]ketanserin from human recombinant serotonin 5-HT2A receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Green Cross

US Patent
LigandPNGBDBM50352661(CHEMBL1823075 | US8835436, Example 122)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]mesulergine from human recombinant 5-HT2C receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Green Cross

Curated by ChEMBL
LigandPNGBDBM50352661(CHEMBL1823075 | US8835436, Example 122)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]impiramine from human serotonin transporter membrane expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed