BDBM50352212 CHEMBL1821761

SMILES CS(=O)(=O)N(CCO)c1ccc(Nc2ncc3cnn(C4CCCCCC4)c3n2)cc1

InChI Key InChIKey=RIEBONGMTZXFMR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352212   

TargetAurora kinase A(Human)
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352212(CHEMBL1821761)
Affinity DataIC50: 13nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50352212(CHEMBL1821761)
Affinity DataIC50: 5nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed