BDBM50351429 CHEMBL450044

SMILES CCOC(=O)OCC1OC(Oc2ccccc2Cc2ccc(OC)cc2)C(O)C(O)C1O

InChI Key InChIKey=QLXKHBNJTPICNF-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50351429   

TargetSolute carrier family 5 member 4(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells assessed as [14C]AMG uptake after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataIC50: 260nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells by [14C]AMG uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cells by [14C]AMG uptake assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataIC50: 7.5nMAssay Description:Inhibition of SGLT2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of SGLT1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSodium/glucose cotransporter 2(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataKi:  151nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetSodium/glucose cotransporter 1(Human)
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50351429(CHEMBL450044)
Affinity DataKi:  7.54E+3nMAssay Description:Inhibition of human SGLT1 expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed