BDBM50350424 CHEMBL454440

SMILES Cc1c(O)c(O)cc2oc3cc(O)cc(O)c3c(=O)c12

InChI Key InChIKey=YPBXGIBBOZOVPM-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50350424   

TargetAurora kinase B(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant Aurora-b assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant ALK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant AKT1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNUAK family SNF1-like kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.56E+4nMAssay Description:Inhibition of recombinant ARK5 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of recombinant AXL assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.52E+4nMAssay Description:Inhibition of recombinant FAK assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of recombinant IGF1-R assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of wild type MEK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of wild type MET assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 8.39E+4nMAssay Description:Inhibition of recombinant NEK2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek6(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 6.78E+4nMAssay Description:Inhibition of recombinant NEK6 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant PIM1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant PLK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase N1(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 4.53E+4nMAssay Description:Inhibition of recombinant PRK1 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant VEGF-R2 assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Heinrich Heine Universit£T

Curated by ChEMBL
LigandPNGBDBM50350424(CHEMBL454440)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of recombinant SRC assessed as 33Pi incorporation after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed