BDBM50350275 CHEMBL1812520

SMILES Clc1ccc2c(\C=C\c3cccnc3)c[nH]c2c1

InChI Key InChIKey=PWUSXYHXDCAKDO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50350275   

TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50350275(CHEMBL1812520)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Namur (Fundp)

Curated by ChEMBL
LigandPNGBDBM50350275(CHEMBL1812520)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human purified TDO assessed as formation of kynurenine from N-formylkynurenine preincubated for 10 mins measured after 5 to 20 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed