BDBM50350069 CHEMBL1813632

SMILES Fc1ccc(cc1)-n1cccc(C(=O)Nc2ccc(Oc3ncnc4scc(-c5ccccc5)c34)c(F)c2)c1=O

InChI Key InChIKey=JSDFIHRUQVWHKK-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50350069   

TargetMacrophage-stimulating protein receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 50nMAssay Description:Inhibition of RONMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 36nMAssay Description:Inhibition of c-Met after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of RETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERBB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-4(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERBB4More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetEphrin type-A receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHA2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetEphrin type-B receptor 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EPHB2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50350069(CHEMBL1813632)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed