BDBM50348558 CHEMBL1801116

SMILES CCNC(=O)C(C)(C)[C@H]1CC2(CCN(CC2)C(=O)[C@@H]2CN(C[C@H]2c2ccc(F)cc2F)C(C)(C)C)c2cc(Cl)c(C)cc12

InChI Key InChIKey=JKQLGKAFSYTJQH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50348558   

TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348558(CHEMBL1801116)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human MC4R expressed in CHO cells assessed as increase of alpha-MSH-stimulated cAMP release pretreated for 10 mins before alpha-M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348558(CHEMBL1801116)
Affinity DataIC50: 3.10nMAssay Description:Displacement of [125I]-NDP-R-MSH from human MC4R expressed in CHO cells after 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed