BDBM50347949 CHEMBL599406::US8637558, 46

SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCCC2)cc1

InChI Key InChIKey=CLEUCPOFSQRVKY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50347949   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50347949(CHEMBL599406 | US8637558, 46)
Affinity DataIC50: 51nMAssay Description:Inhibition of human GST-fused 15-PGDH expressed in Escherichia coli BL21 using PGE2 as substrate assessed as formation of NADH by fluorescence spectr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50347949(CHEMBL599406 | US8637558, 46)
Affinity DataIC50: 50.9nMpH: 7.5Assay Description:Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2014
Entry Details
Go to US Patent

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50347949(CHEMBL599406 | US8637558, 46)
Affinity DataIC50: 51nMAssay Description:Inhibition of human 15-PGDH expressed in Escherichia coli using PGE2 as substrate and NAD+ as coenzyme assessed as formation of NADH by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50347949(CHEMBL599406 | US8637558, 46)
Affinity DataIC50: 51nMAssay Description:Inhibition of PGDH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50347949(CHEMBL599406 | US8637558, 46)
Affinity DataIC50: 51nMAssay Description:Inhibition of human 15PGDH expressed in Escherichia coli BL-21 by fluorescence spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed