BDBM50347746 CHEMBL1803085
SMILES Oc1ccc(NC2=NC(=Cc3ccc4OCOc4c3)C(=O)N2)cc1
InChI Key InChIKey=VRGNMDTYOWQXQC-UHFFFAOYSA-N
Data 17 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50347746
TargetDual specificity protein kinase CLK3(Mouse)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of GST-fused mouse recombinant CLK3 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha 3(Human)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant CK2 using RRRDDDSDDD peptide as substrate incubated for 30 mins in presence of ATP by scintillation counting methodMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant Pim1 expressed in Escherichia coli using histone H1 as substrate incubated for 30 mins in presence of ATP by scintill...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of GST-fused human recombinant DYRK3 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of GST-fused human recombinant DYRK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presen...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of GST-fused human recombinant DYRK1B expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of GST-fused human recombinant DYRK1A expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in prese...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK2(Mouse)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of mouse recombinant GST-fused CLK2 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Mouse)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-fused mouse recombinant CLK1 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
Universite£? De Rennes 1
Curated by ChEMBL
Universite£? De Rennes 1
Curated by ChEMBL
Affinity DataIC50: 96nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Mouse)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of porcine brain GSK-3alpha/beta using YRRAAVPPSPSLSRHSSPHQpSEDEEE as substrate incubated for 30 mins in presence of ATP by scintillation ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant GST-tagged DYRK2 using KKISGRLSPIMTEQ as substrate and [gamma32]-ATP after 30 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Human)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant Pim1More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK3(Mouse)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK3 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK1(Mouse)
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Manros Therapeutics & Perha Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK1 using GRSRSRSRSRSR as substrateMore data for this Ligand-Target Pair