BDBM50347546 CHEMBL1801951::US10434085, Compound LL-Z164-1

SMILES C[C@H]1CCCC(=O)[C@H]([C@H](C/C=C/c2cc(cc(c2C(=O)O1)O)OC)O)O

InChI Key InChIKey=WFIUAGOQGGAREU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50347546   

TargetMitogen-activated protein kinase kinase kinase 7(Human)
University of North Carolina At Greensboro

Curated by ChEMBL
LigandPNGBDBM50347546(CHEMBL1801951 | US10434085, Compound LL-Z164-1)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of TAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2016
Entry Details Article
PubMed
TargetTranscription factor p65(Human)
University of North Carolina At Greensboro

Curated by ChEMBL
LigandPNGBDBM50347546(CHEMBL1801951 | US10434085, Compound LL-Z164-1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of NFkappa p65 isolated from nuclear extract of human HeLa cells by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50347546(CHEMBL1801951 | US10434085, Compound LL-Z164-1)
Affinity DataIC50: 2.60E+3nMAssay Description:The assay was performed at BSP Biosience Inc. (5Z)-7-oxozeaenol was used as a positive control. Analogue 3 was not tested due to the short-term stabi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details
Go to US Patent