BDBM50346803 CHEMBL1795862

SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N1Cc2ccccc2C[C@@H]1C(=O)NO

InChI Key InChIKey=OTEWYJZEFZRZKI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50346803   

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50: 112nMAssay Description:Inhibition of human MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50: 11nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50: 30nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-25(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346803(CHEMBL1795862)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed