BDBM50346798 CHEMBL1795857

SMILES CCCCc1ccc(cc1)C#Cc1ccc(s1)S(=O)(=O)N[C@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)NO

InChI Key InChIKey=VZNWQFCLBMVARX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50346798   

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50: 63nMAssay Description:Inhibition of human MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50: 180nMAssay Description:Inhibition of human MMP3 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50: 490nMAssay Description:Inhibition of human MMP8 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-25(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50346798(CHEMBL1795857)
Affinity DataIC50: 38nMAssay Description:Inhibition of human MMP25 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed