BDBM50346042 8-methoxy-2-methyl-5-(2-(pyridin-2-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole::CHEMBL1783955

SMILES COc1ccc2n(CCc3ccccn3)c3CCN(C)Cc3c2c1

InChI Key InChIKey=YIVBCXIAPLXDDK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346042   

TargetHistamine H1 receptor(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50346042(8-methoxy-2-methyl-5-(2-(pyridin-2-yl)ethyl)-2,3,4...)
Affinity DataIC50: 4.67E+3nMAssay Description:Antagonist activity at human histamine H1 receptor in SK-N-SH cells assessed as inhibition of histamine-induced calcium level increase during phase-1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50346042(8-methoxy-2-methyl-5-(2-(pyridin-2-yl)ethyl)-2,3,4...)
Affinity DataIC50: 8.36E+3nMAssay Description:Antagonist activity at human recombinant 5-HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced intracellular cAMP accu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed