BDBM50345591 3-((2-(cyclopropylamino)pyrimidin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide::CHEMBL1784630

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc(NC4CC4)nc3)cc2C(F)(F)F)CC1

InChI Key InChIKey=IZPFISNXGGICOO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345591   

TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50345591(3-((2-(cyclopropylamino)pyrimidin-5-yl)ethynyl)-4-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of wild type human ABL using [EAIYAAPFAKKK] peptide substrate by Hotspot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed