BDBM50345349 (2S,3R,4R,5S,6R)-2-(4-Chloro-2-ethoxy-5-((5-(thiophen-2-yl)thiazol-2-yl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2Hpyran-3,4,5-triol::CHEMBL1784281

SMILES CCOc1cc(Cl)c(Cc2ncc(s2)-c2cccs2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=SKCQQTVRKQJWBU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345349   

TargetSodium/glucose cotransporter 2(Human)
Green Cross Corporation Research Center

Curated by ChEMBL
LigandPNGBDBM50345349((2S,3R,4R,5S,6R)-2-(4-Chloro-2-ethoxy-5-((5-(thiop...)
Affinity DataIC50: 4.29nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]-alpha-methyl-D-glucopyranoside uptake after 2 hrs by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed