BDBM50344278 (R)-quinuclidin-3-yl butyl(thiophen-2-ylmethyl)carbamate::CHEMBL1779041

SMILES CCCCN(Cc1cccs1)C(=O)O[C@H]1CN2CCC1CC2

InChI Key InChIKey=CZTMYBUHNDAZEH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344278   

TargetMuscarinic acetylcholine receptor M1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344278((R)-quinuclidin-3-yl butyl(thiophen-2-ylmethyl)car...)
Affinity DataIC50: 0.800nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344278((R)-quinuclidin-3-yl butyl(thiophen-2-ylmethyl)car...)
Affinity DataIC50: 17.7nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344278((R)-quinuclidin-3-yl butyl(thiophen-2-ylmethyl)car...)
Affinity DataIC50: 76.2nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed