BDBM50344211 CHEMBL1778713::ethyl 4-(4-(4-chlorophenylamino)pteridin-2-ylamino)benzoate

SMILES CCOC(=O)c1ccc(Nc2nc(Nc3ccc(Cl)cc3)c3nccnc3n2)cc1

InChI Key InChIKey=XTPOPDGVENHAMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344211   

TargetALK tyrosine kinase receptor(Human)
Pharmadesign

Curated by ChEMBL
LigandPNGBDBM50344211(ethyl 4-(4-(4-chlorophenylamino)pteridin-2-ylamino...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of ALK using FL-Peptide 13, 5-FAM-KKSRGDYMTMQIG-CONH2 substrate after 60 mins by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed