BDBM50343365 4-[2,4-Dichloro-6-(4,4,4-trifluoro-butoxy)-phenyl]-6-methyl-pyrimidin-2-ylamine::CHEMBL1774835

SMILES Cc1cc(nc(N)n1)-c1c(Cl)cc(Cl)cc1OCCCC(F)(F)F

InChI Key InChIKey=GBFWYMWIESHQSG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343365   

TargetHeat shock protein HSP 90-alpha(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343365(4-[2,4-Dichloro-6-(4,4,4-trifluoro-butoxy)-phenyl]...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed
LigandPNGBDBM50343365(4-[2,4-Dichloro-6-(4,4,4-trifluoro-butoxy)-phenyl]...)
Affinity DataKi:  1.16E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2013
Entry Details Article
PubMed