BDBM50343147 CHEMBL1773180::N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)piperazin-1-yl)-1-(thiophen-2-yl)propan-2-yl)oxalamide

SMILES COc1ccc(cc1)N1CCN(CC1)C(C(C)NC(=O)C(=O)NCc1ccco1)c1cccs1

InChI Key InChIKey=QAXOVMMDPXUGKF-UHFFFAOYSA-N

Data  1 KI  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50343147   

TargetDual specificity protein phosphatase 3(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human VHR expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase beta(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human PTPB expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase CDC14A(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Cdc14A expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 3(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PRL3 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetProtein tyrosine phosphatase type IVA 1(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PRL1 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MKP3 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase alpha(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human PTPalpha expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human LAR expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 9(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human MEG2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human FAP1 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 22(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human Lyp expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human SHP2 expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPB expressed in Escherichia coli after 5 mins by microplate spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343147(N1-(furan-2-ylmethyl)-N2-(1-(4-(4-methoxyphenyl)pi...)
Affinity DataKi:  3.20E+3nMAssay Description:Competitive inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB assessed as production of p-nitrophenol from pNPP substrate by Linew...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed