BDBM50342140 3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminophenyl)-propionicAcid Methyl Ester::CHEMBL1766000

SMILES COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1ccnc1

InChI Key InChIKey=XJNXEEASXBUDAQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342140   

TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342140(3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminopheny...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP26A1 in human MCF7 cell microsomes using [3H]ATRA after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetCytochrome P450 26A1(Human)
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50342140(3-Imidazol-1-yl-2,2-dimethyl-3-(4-phenylaminopheny...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CYP26A1-mediated retinoic acid metabolism in human MCF7 cell microsomes using [3H]ATRA as substrate after 1 hr by scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed