BDBM50342002 (2S,3aR,6S,6aR)-N-(cyclohexylmethyl)-6-(5-((R)-3-(pyrrolidin-1-ylmethyl)phenyl)-1H-tetrazol-1-yl)hexahydrofuro[3,2-b]furan-2-amine::(2S,3aR,6S,6aR)-N-(cyclohexylmethyl)-6-(5-(3-(pyrrolidin-1-ylmethyl)phenyl)-1H-tetrazol-1-yl)hexahydrofuro[3,2-b]furan-2-amine::CHEMBL472003

SMILES C(N[C@@H]1C[C@H]2OC[C@@H]([C@H]2O1)n1nnnc1-c1cccc(CN2CCCC2)c1)C1CCCCC1

InChI Key InChIKey=LFRRGQXSMKOSOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342002   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342002((2S,3aR,6S,6aR)-N-(cyclohexylmethyl)-6-(5-((R)-3-(...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of SHP-2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342002((2S,3aR,6S,6aR)-N-(cyclohexylmethyl)-6-(5-((R)-3-(...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of SHP2 catalytic domain (unknown origin) using p-nitrophenyl phosphate as substrate incubated for 10 to 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Max Planck Institute of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM50342002((2S,3aR,6S,6aR)-N-(cyclohexylmethyl)-6-(5-((R)-3-(...)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of SHP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed