BDBM50341876 CHEMBL1767063::E-3-(1-Oxoisoquinolin-5-yl)propenoic acid

SMILES OC(=O)\C=C\c1cccc2c1cc[nH]c2=O

InChI Key InChIKey=NHJNBEMBWRRWAC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341876   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50341876(E-3-(1-Oxoisoquinolin-5-yl)propenoic acid | CHEMBL...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of full length human PARP-1 after 10 mins by FlashPlate scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50341876(E-3-(1-Oxoisoquinolin-5-yl)propenoic acid | CHEMBL...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed