BDBM50341866 5-(4-Chlorobenzamido)isoquinolin-1-one::CHEMBL1767051

SMILES Clc1ccc(cc1)C(=O)Nc1cccc2c1cc[nH]c2=O

InChI Key InChIKey=PBTMIZWLECDGNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341866   

TargetPoly [ADP-ribose] polymerase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50341866(5-(4-Chlorobenzamido)isoquinolin-1-one | CHEMBL176...)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of full length human PARP-1 after 10 mins by FlashPlate scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 2(Mouse)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50341866(5-(4-Chlorobenzamido)isoquinolin-1-one | CHEMBL176...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed