BDBM50341553 (E)-2-(Pyridin-2-ylmethylene)hydrazinecarbothioamide::2-(pyridin-2-ylmethylene)hydrazinecarbothioamide::Beta-pyridine-2yl thiosemicarbazone::CHEMBL25988

SMILES NC(=S)NN=Cc1ccccn1

InChI Key InChIKey=GXBCCUBTQFNGFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50341553   

TargetDNA topoisomerase 2-alpha(Human)
Memorial Sloan-Kettering Cancer Center

Curated by ChEMBL
LigandPNGBDBM50341553((E)-2-(Pyridin-2-ylmethylene)hydrazinecarbothioami...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human topoisomerase 2 alpha-mediated relaxation of supercoiled pHOT DNA after 30 mins by agarose gel electrophoresisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Universite Grenoble

Curated by ChEMBL
LigandPNGBDBM50341553((E)-2-(Pyridin-2-ylmethylene)hydrazinecarbothioami...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase using L-DOPA as substrate preincubated for 5 mins by spectroscopic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed