BDBM50341331 CHEMBL1766489::rel-(1R,2S,4R,5S)-6-[[1-(10-Hydroxydecyl)-1H-1,2,3-triazol-4-yl]methylamino]cyclohexane-1,2,3,4,5-pentaol

SMILES OCCCCCCCCCCn1cc(CN[C@@H]2[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)[C@H]2O)nn1

InChI Key InChIKey=JZEYDOMKWQQKCY-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50341331   

TargetLysosomal acid glucosylceramidase(Human)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341331(rel-(1R,2S,4R,5S)-6-[[1-(10-Hydroxydecyl)-1H-1,2,3...)
Affinity DataIC50: 2.19E+3nMpH: 5.2Assay Description:Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 5.2 after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341331(rel-(1R,2S,4R,5S)-6-[[1-(10-Hydroxydecyl)-1H-1,2,3...)
Affinity DataIC50: 1.30E+3nMpH: 7.4Assay Description:Inhibition of recombinant glucocerebrosidase in McIlvaine buffer at pH 7.4 after 10 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetBeta-galactosidase(Bovine)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341331(rel-(1R,2S,4R,5S)-6-[[1-(10-Hydroxydecyl)-1H-1,2,3...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of bovine liver beta-galactosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetOligo-1,6-glucosidase IMA1(Baker's yeast)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341331(rel-(1R,2S,4R,5S)-6-[[1-(10-Hydroxydecyl)-1H-1,2,3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of yeast alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProbable alpha-glucosidase Os06g0675700(Rice)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341331(rel-(1R,2S,4R,5S)-6-[[1-(10-Hydroxydecyl)-1H-1,2,3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rice alpha-glucosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetAlpha-galactosidase(Arabian coffee)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341331(rel-(1R,2S,4R,5S)-6-[[1-(10-Hydroxydecyl)-1H-1,2,3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of alpha-galactosidase from coffee beansMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Spanish National Research Council (Consejo Superior De Investigaciones Cienti£?Ficas)

Curated by ChEMBL
LigandPNGBDBM50341331(rel-(1R,2S,4R,5S)-6-[[1-(10-Hydroxydecyl)-1H-1,2,3...)
Affinity DataKi:  890nMAssay Description:Competitive inhibition of recombinant glucocerebrosidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed