BDBM50341059 3-(1-(4-amino-1,3,5-triazin-2-yl)-1H-benzo[d]imidazol-2-ylamino)phenol::CHEMBL1762778
SMILES Nc1ncnc(n1)-n1c(Nc2cccc(O)c2)nc2ccccc12
InChI Key InChIKey=JVMUZOHLNVZUFA-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50341059
Affinity DataIC50: 21nMAssay Description:Inhibition of mTOR assessed as inhibition of phosphorylation of 4EBP1 by Lantha-Screen enzyme assayMore data for this Ligand-Target Pair
Affinity DataIC50: 710nMAssay Description:Inhibition of mTOR in human U-87 cells assessed as inhibition of phosphorylation of 4EBP1 at T37/46More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of mTOR in human U-87 cells assessed as inhibition of phosphorylation of AKT at S473More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair