BDBM50340930 1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-(4-methoxyphenyl)urea::CHEMBL1761934::N-{4-[6,7-Dimethoxy-quinazolin-4-ylamino]phenyl}-N'-(4-methoxyphenyl)urea (11e)

SMILES COc1ccc(NC(=O)Nc2ccc(Nc3ncnc4cc(OC)c(OC)cc34)cc2)cc1

InChI Key InChIKey=XENAFWVEGOOYMA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50340930   

TargetEpidermal growth factor receptor(Human)
Universit�� Lille Nord De France

LigandPNGBDBM50340930(1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-...)
Affinity DataIC50: 3.45E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Universit�� Lille Nord De France

LigandPNGBDBM50340930(1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-...)
Affinity DataIC50: 7.56E+4nMpH: 7.5Assay Description:Kinase assays were performed in 96-well plates (Multiscreen Durapore, Millipore) using [γ-32P]ATP (Amersham Biosciences) and the synthetic polym...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Universit�� Lille Nord De France

LigandPNGBDBM50340930(1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Universit�� Lille Nord De France

LigandPNGBDBM50340930(1-(4-(6,7-dimethoxyquinazolin-4-ylamino)phenyl)-3-...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant human VEGFR-2-mediated poly(Glu4Tyr) phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed