BDBM50340728 2-{[5,7-Dimethyl-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-2-yl]oxy}ethanol::CHEMBL1762571::US8552005, 1.1(2)

SMILES Cc1cc(C)n2nc(OCCO)c(c2n1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=KMJQPKBOBYLTBC-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340728   

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340728(US8552005, 1.1(2) | CHEMBL1762571 | 2-{[5,7-Dimeth...)
Affinity DataKi:  22.2nMAssay Description:Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340728(US8552005, 1.1(2) | CHEMBL1762571 | 2-{[5,7-Dimeth...)
Affinity DataKi:  222nM IC50: 477nMAssay Description:Radioligand binding assay using 5-HT6 receptors.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2014
Entry Details
Go to US Patent

Target5-hydroxytryptamine receptor 6(Human)
Chemical Diversity Research Institute

Curated by ChEMBL
LigandPNGBDBM50340728(US8552005, 1.1(2) | CHEMBL1762571 | 2-{[5,7-Dimeth...)
Affinity DataKi:  283nMAssay Description:Antagonist activity at human recombinant 5HT6 receptor expressed in HEK293 cells assessed as inhibition of serotonin-induced cAMP production after 2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed