BDBM50340432 (4-(1H-imidazol-4-yl)piperidin-1-yl)(3-methyl-2H-benzo[b][1,4]oxazin-4(3H)-yl)methanone::CHEMBL1761843

SMILES CC1COc2ccccc2N1C(=O)N1CCC(CC1)c1cnc[nH]1

InChI Key InChIKey=IKCNXAIMXSHWAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50340432   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340432((4-(1H-imidazol-4-yl)piperidin-1-yl)(3-methyl-2H-b...)
Affinity DataIC50: 72nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabeled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340432((4-(1H-imidazol-4-yl)piperidin-1-yl)(3-methyl-2H-b...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant 11beta-HSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Sanofi-Aventis R&D

Curated by ChEMBL
LigandPNGBDBM50340432((4-(1H-imidazol-4-yl)piperidin-1-yl)(3-methyl-2H-b...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabeled-cortisone to cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2011
Entry Details Article
PubMed