BDBM50339461 3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid::CHEMBL1688458

SMILES OC(=O)CCc1ccc(OCc2cccc(Oc3ccccc3)c2)cc1

InChI Key InChIKey=BWNUDKFBKGPSBH-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50339461   

TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50339461(3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...)
Affinity DataEC50:  34nMAssay Description:Agonist activity against human GPR40 expressed in CHO cells assessed as increase in intracellular calcium level by FLIPR assay in presence of 0.1% BS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50339461(3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...)
Affinity DataEC50:  63.1nMAssay Description:Agonist activity at FFAR1 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 30 mins by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50339461(3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...)
Affinity DataEC50:  562nMAssay Description:Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
University of Southern Denmark

Curated by ChEMBL
LigandPNGBDBM50339461(3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...)
Affinity DataEC50:  968nMAssay Description:Agonist activity at human FFA4 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50339461(3-{4-[(3-Phenoxybenzyl)oxy]phenyl}propanoic Acid |...)
Affinity DataEC50:  57nMAssay Description:Agonist activity at human FFA1 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/15/2019
Entry Details Article
PubMed