BDBM50338753 (S)-N1-(2-((S)-5-amino-1-((S)-1-((2S,3S)-1-amino-3-methyl-1-oxopentan-2-ylamino)-3-(1H-imidazol-5-yl)-1-oxopropan-2-ylamino)-1,5-dioxopentan-2-ylamino)-2-oxoethyl)-2-((S)-2-((S)-1-((4S,7S,10S,13S)-17-amino-10-sec-butyl-7-(3-guanidinopropyl)-4-(2-(methylthio)ethyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazaheptadecanecarbonyl)pyrrolidine-2-carboxamido)-3-(1H-imidazol-5-yl)propanamido)pentanediamide::CHEMBL1684365

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCSC)NC(C)=O)[C@@H](C)CC)C(N)=O

InChI Key InChIKey=MDEBWIXAVYLVGJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50338753   

TargetVascular endothelial growth factor receptor 1(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50338753((S)-N1-(2-((S)-5-amino-1-((S)-1-((2S,3S)-1-amino-3...)
Affinity DataIC50: 1.03E+5nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1 domain 1 to 7 after 3 hrs by chemiluminescent competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50338753((S)-N1-(2-((S)-5-amino-1-((S)-1-((2S,3S)-1-amino-3...)
Affinity DataIC50: 1.60E+5nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1 domain 1 to 3 after 3 hrs by chemiluminescent competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50338753((S)-N1-(2-((S)-5-amino-1-((S)-1-((2S,3S)-1-amino-3...)
Affinity DataIC50: 1.03E+5nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1 whole extracellular domain after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Instituto De Qu£Mica M£Dica

Curated by ChEMBL
LigandPNGBDBM50338753((S)-N1-(2-((S)-5-amino-1-((S)-1-((2S,3S)-1-amino-3...)
Affinity DataIC50: 1.60E+5nMAssay Description:Displacement of biotinylated VEGF165 from human recombinant VEGFR1 D1-D3 domain after 3 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed