BDBM50338293 CHEMBL1682015::N-(4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide

SMILES O=C(CN1C(=O)CCc2ccccc12)Nc1scc(C#N)c1-c1nnc[nH]1

InChI Key InChIKey=WNRCGOJLZOLSJN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338293   

TargetMitogen-activated protein kinase 9(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338293(N-(4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant JNK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338293(N-(4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant JNK1 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338293(N-(4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant p38alpha after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338293(N-(4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant ERK2 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Elan Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50338293(N-(4-cyano-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl)...)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant JNK3 after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed