BDBM50337832 CHEMBL1683873::N-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)cyclopropanamine::US10562878, Compound 78

SMILES Clc1ccc(cc1Cl)C1(CNC2CC2)CCCCC1

InChI Key InChIKey=VAXCWNURWRJNKL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337832   

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337832(N-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)cyclop...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337832(N-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)cyclop...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant Norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337832(N-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)cyclop...)
Affinity DataIC50: 651nMAssay Description:Inhibition of human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337832(N-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)cyclop...)
Affinity DataIC50: 651nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetNeuroepithelial cell-transforming gene 1 protein(Human)
Sunovion Pharamceuticals

US Patent
LigandPNGBDBM50337832(N-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)cyclop...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetSodium-dependent dopamine transporter(Human)
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337832(N-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)cyclop...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
US Patent