BDBM50337381 CHEMBL1682556::N-cyclohexyl-6-(1H-indazol-5-yl)imidazo[2,1-b]thiazol-5-amine

SMILES C1CCC(CC1)Nc1c(nc2sccn12)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=HENXDAXZQIPSPS-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50337381   

TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337381(N-cyclohexyl-6-(1H-indazol-5-yl)imidazo[2,1-b]thia...)
Affinity DataKi:  622nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337381(N-cyclohexyl-6-(1H-indazol-5-yl)imidazo[2,1-b]thia...)
Affinity DataKi:  642nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337381(N-cyclohexyl-6-(1H-indazol-5-yl)imidazo[2,1-b]thia...)
Affinity DataKi:  1.29E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337381(N-cyclohexyl-6-(1H-indazol-5-yl)imidazo[2,1-b]thia...)
Affinity DataKi:  5.34E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337381(N-cyclohexyl-6-(1H-indazol-5-yl)imidazo[2,1-b]thia...)
Affinity DataKi:  1.80E+6nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed