BDBM50337373 4-(1H-indazol-5-yl)-N,5-diphenylthiazol-2-amine::CHEMBL1682548

SMILES N(c1nc(c(s1)-c1ccccc1)-c1ccc2[nH]ncc2c1)c1ccccc1

InChI Key InChIKey=TYVWUBVBBNANOO-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337373   

TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337373(4-(1H-indazol-5-yl)-N,5-diphenylthiazol-2-amine | ...)
Affinity DataKi:  1.41E+3nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337373(4-(1H-indazol-5-yl)-N,5-diphenylthiazol-2-amine | ...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337373(4-(1H-indazol-5-yl)-N,5-diphenylthiazol-2-amine | ...)
Affinity DataKi: >4.90E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337373(4-(1H-indazol-5-yl)-N,5-diphenylthiazol-2-amine | ...)
Affinity DataKi: >5.45E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337373(4-(1H-indazol-5-yl)-N,5-diphenylthiazol-2-amine | ...)
Affinity DataKi: >8.75E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337373(4-(1H-indazol-5-yl)-N,5-diphenylthiazol-2-amine | ...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed