BDBM50337369 CHEMBL1682544::N-ethyl-4-(1H-indazol-5-yl)thiazol-2-amine

SMILES CCNc1nc(cs1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=PYHCYHNXLIEWSB-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337369   

TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337369(N-ethyl-4-(1H-indazol-5-yl)thiazol-2-amine | CHEMB...)
Affinity DataKi:  888nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337369(N-ethyl-4-(1H-indazol-5-yl)thiazol-2-amine | CHEMB...)
Affinity DataKi:  1.95E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337369(N-ethyl-4-(1H-indazol-5-yl)thiazol-2-amine | CHEMB...)
Affinity DataKi:  3.41E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337369(N-ethyl-4-(1H-indazol-5-yl)thiazol-2-amine | CHEMB...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337369(N-ethyl-4-(1H-indazol-5-yl)thiazol-2-amine | CHEMB...)
Affinity DataKi:  3.93E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337369(N-ethyl-4-(1H-indazol-5-yl)thiazol-2-amine | CHEMB...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed