BDBM50337368 4-(1H-indazol-5-yl)thiazol-2-amine::CHEMBL1682543

SMILES Nc1nc(cs1)-c1ccc2[nH]ncc2c1

InChI Key InChIKey=IHKNEMYSHFRMOS-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50337368   

TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337368(4-(1H-indazol-5-yl)thiazol-2-amine | CHEMBL1682543)
Affinity DataKi:  909nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337368(4-(1H-indazol-5-yl)thiazol-2-amine | CHEMBL1682543)
Affinity DataKi:  2.13E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337368(4-(1H-indazol-5-yl)thiazol-2-amine | CHEMBL1682543)
Affinity DataKi:  2.90E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337368(4-(1H-indazol-5-yl)thiazol-2-amine | CHEMBL1682543)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337368(4-(1H-indazol-5-yl)thiazol-2-amine | CHEMBL1682543)
Affinity DataKi:  4.47E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337368(4-(1H-indazol-5-yl)thiazol-2-amine | CHEMBL1682543)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed