BDBM50337365 2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidine::CHEMBL1682540

SMILES c1n[nH]c2ccc(cc12)-c1cn2cccnc2n1

InChI Key InChIKey=CPGKMMMSMJKHDL-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50337365   

TargetGlycogen synthase kinase-3 beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337365(2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidine | CHEM...)
Affinity DataKi:  141nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetRho-associated protein kinase 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337365(2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidine | CHEM...)
Affinity DataKi:  226nMAssay Description:Inhibition of Rock2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337365(2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidine | CHEM...)
Affinity DataKi:  1.66E+3nMAssay Description:Inhibition of Pim1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEpidermal growth factor receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337365(2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidine | CHEM...)
Affinity DataKi: >1.80E+3nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase PAK 4(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337365(2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidine | CHEM...)
Affinity DataKi: >3.75E+3nMAssay Description:Inhibition of Pak4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337365(2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidine | CHEM...)
Affinity DataKi: >4.90E+3nMAssay Description:Inhibition of aurora 2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50337365(2-(1H-indazol-5-yl)imidazo[1,2-a]pyrimidine | CHEM...)
Affinity DataKi: >8.88E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed