BDBM50336490 3,5-DIHYDROXYBENZOATE::3,5-Dihydroxy-benzoic acid::3,5-Dihydroxybenzoate, IX::3,5-dihydroxybenzoic acid::3,5-dihydroxybenzoicacid::CHEMBL95308

SMILES OC(=O)c1cc(O)cc(O)c1

InChI Key InChIKey=UYEMGAFJOZZIFP-UHFFFAOYSA-N

Data  8 KI  2 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50336490   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PTP1B expressed in CHO cells assessed as p-nitorphenol production after 2 mins by microplate readerMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataEC50:  3.77E+5nMAssay Description:Agonist activity at human recombinant GPR81 transfected in african green monkey COS-7 cells after 20 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human recombinant GPR109a transfected in african green monkey COS-7 cells after 20 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetToll-like receptor 2(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataIC50: 1.17E+5nMAssay Description:Antagonist activity at TLR2 in mouse RAW264.7 cells assessed as PAM3CSK4-induced NO production measured after 24 hrs by Griess assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Calgary

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  510nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Calgary

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  550nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  650nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase(European seabass)
Gumushane University

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  2.13E+3nMAssay Description:Inhibition of Dicentrarchus labrax CA using 4-nitrophenylacetate substrate by esterase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Calgary

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  3.67E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Calgary

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  4.41E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  7.17E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProlyl 4-hydroxylase subunit alpha-1(Chicken)
University of Oulu

LigandPNGBDBM50336490(3,5-dihydroxybenzoic acid | 3,5-dihydroxybenzoicac...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibition assay using procollagen-prolin, 2-oxoglutarate 4-dioxygenase.More data for this Ligand-Target Pair
In DepthDetails
PubMed