BDBM50336487 3,4-Dimethoxy-benzoic acid::3,4-dimethoxybenzoic acid::CHEMBL118903

SMILES COc1ccc(cc1OC)C(O)=O

InChI Key InChIKey=DAUAQNGYDSHRET-UHFFFAOYSA-N

Data  8 KI  3 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50336487   

TargetAlpha-(1,3)-fucosyltransferase 7(Human)
Schering-Plough Research Institute

LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataIC50: 2.00E+5nMpH: 7.3 T: 2°CAssay Description:A radioligand-binding assay was developed using scintillation proximity assay (SPA) technology. The wheat germ agglutinin SPA beads (Amersham) (0.2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/10/2012
Entry Details Article
PubMed
TargetAlpha-glucosidase MAL12(Baker's yeast)
Kinki University

LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataIC50: 3.00E+5nMpH: 7.0 T: 2°CAssay Description:α-glucosidase (25 μL, 0.2 U/mL), 25 μL of various concentrations of samples, and 175 μL of 50 mM sodium phosphate buffer (pH 7.0)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
Kinki University

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate preincubated for 10 mins followed by enzyme addition measured after 20 mins by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataKi:  740nMAssay Description:Inhibition of human carbonic anhydrase 14 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
University of Calgary

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataKi:  6.18E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataKi:  6.48E+3nMAssay Description:Inhibition of human CA4 using 4NPA as substrate for 3 mins by Lineweaver burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Calgary

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataKi:  6.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Calgary

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataKi:  6.83E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataKi:  7.15E+3nMAssay Description:Inhibition of human carbonic anhydrase 7 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Calgary

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataKi:  8.25E+3nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50336487(3,4-dimethoxybenzoic acid | CHEMBL118903 | 3,4-Dim...)
Affinity DataKi:  2.44E+4nMAssay Description:Inhibition of human CA6 using 4NPA as substrate for 3 mins by Lineweaver burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed