BDBM50336229 (+/-)-4-(3,5-dimethylpiperidin-1-ylsulfonyl)-3-fluoro-N-(3-methoxyphenyl)benzamide::CHEMBL1669632

SMILES COc1cccc(NC(=O)c2ccc(c(F)c2)S(=O)(=O)N2CC(C)CC(C)C2)c1

InChI Key InChIKey=XCYPPUAPQPUXSG-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50336229   

TargetTrace amine-associated receptor 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336229((+/-)-4-(3,5-dimethylpiperidin-1-ylsulfonyl)-3-flu...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at mouse TAAR1 assessed as reversal of endogenous beta-PEA effectMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336229((+/-)-4-(3,5-dimethylpiperidin-1-ylsulfonyl)-3-flu...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human TAAR1 assessed as reversal of endogenous beta-PEA effectMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336229((+/-)-4-(3,5-dimethylpiperidin-1-ylsulfonyl)-3-flu...)
Affinity DataKi:  4nMAssay Description:Inhibition of mouse TAAR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Rat)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336229((+/-)-4-(3,5-dimethylpiperidin-1-ylsulfonyl)-3-flu...)
Affinity DataKi:  1.39E+3nMAssay Description:Inhibition of rat TAAR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed
TargetTrace amine-associated receptor 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50336229((+/-)-4-(3,5-dimethylpiperidin-1-ylsulfonyl)-3-flu...)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of human TAAR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2011
Entry Details Article
PubMed