BDBM50336150 (1R,3S)-4-chloro-5-(3,4-difluorophenyl)-N-(3-hydroxycyclopentyl)isoxazole-3-carboxamide::CHEMBL1669538

SMILES O[C@H]1CC[C@H](C1)NC(=O)c1noc(c1Cl)-c1ccc(F)c(F)c1

InChI Key InChIKey=MVLHTVAMAHQSAI-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50336150   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Merck Sharpe and Dohme

Curated by ChEMBL

LigandBDBM50336150((1R,3S)-4-chloro-5-(3,4-difluorophenyl)-N-(3-hydro...)Copy SMILESCopy InChI

Affinity DataIC50: 404nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of capsaicin-induced calcium influx by fluorimetric assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/23/2011
Entry Details Article
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