BDBM50335398 CHEMBL1651551::N-Heptyl-1-deoxynojirimycin

SMILES CCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key InChIKey=MBQCNYZEYQQTEE-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50335398   

TargetLysosomal acid glucosylceramidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(N-Heptyl-1-deoxynojirimycin | CHEMBL1651551)
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of recombinant GBA1 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(N-Heptyl-1-deoxynojirimycin | CHEMBL1651551)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(N-Heptyl-1-deoxynojirimycin | CHEMBL1651551)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-galactosidase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(N-Heptyl-1-deoxynojirimycin | CHEMBL1651551)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of lactase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(N-Heptyl-1-deoxynojirimycin | CHEMBL1651551)
Affinity DataIC50: 500nMAssay Description:Inhibition of sucrase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335398(N-Heptyl-1-deoxynojirimycin | CHEMBL1651551)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant GBA2 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50335398(N-Heptyl-1-deoxynojirimycin | CHEMBL1651551)
Affinity DataKi:  95nMAssay Description:Inhibition of human GAA using 4-methylumbelliferyl-alpha-D-glucopyranoside as substrate preincubated for 45 min followed by substrate addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed