BDBM50335391 CHEMBL1651629::N-Pentoxypentyl-1-deoxynojirimycin

SMILES CCCCCOCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key InChIKey=LLUQYJRYJAPGMA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50335391   

TargetLysosomal acid glucosylceramidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335391(N-Pentoxypentyl-1-deoxynojirimycin | CHEMBL1651629)
Affinity DataIC50: 7.05E+5nMAssay Description:Inhibition of recombinant GBA1 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetCeramide glucosyltransferase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335391(N-Pentoxypentyl-1-deoxynojirimycin | CHEMBL1651629)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335391(N-Pentoxypentyl-1-deoxynojirimycin | CHEMBL1651629)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-galactosidase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335391(N-Pentoxypentyl-1-deoxynojirimycin | CHEMBL1651629)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of lactase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335391(N-Pentoxypentyl-1-deoxynojirimycin | CHEMBL1651629)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of sucrase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335391(N-Pentoxypentyl-1-deoxynojirimycin | CHEMBL1651629)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant GBA2 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed