BDBM50335387 CHEMBL1651633::N-Nonoxypentyl-1-deoxynojirimycin

SMILES CCCCCCCCCOCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChI Key InChIKey=SXPLUAKSZJTQBC-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50335387   

TargetCeramide glucosyltransferase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal acid glucosylceramidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant GBA1 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetLysosomal alpha-glucosidase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of maltase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetBeta-galactosidase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of lactase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSucrase-isomaltase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of sucrase in mouse intestinal input by glucose release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant GBA2 preincubated with compound for 30 mins using 4-methylumbelliferyl-B-glucoside substrate by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetNon-lysosomal glucosylceramidase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50335387(N-Nonoxypentyl-1-deoxynojirimycin | CHEMBL1651633)
Affinity DataIC50: 34nMAssay Description:Inhibition of NLGase in human SH-SY5Y cells using MUG-Gluc as fluorogenic substrate preincubated for 30 mins followed by substrate addition and measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed