BDBM50334998 3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazole::CHEMBL1649949

SMILES Cc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1ccccc1

InChI Key InChIKey=LPJNRJXWXMNHIA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334998   

TargetVasopressin V1a receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50334998(3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human V1A receptor expressed in CHO cells assessed as inhibition of AVP-induced intracellular calcium release after 30 seconds...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50334998(3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of [3H]glycine uptake at GlyT2 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50334998(3-Biphenyl-4-yl-5-methyl-4-phenyl-4H-1,2,4-triazol...)
Affinity DataIC50: 880nMAssay Description:Inhibition of [3H]glycine uptake at GlyT1 in rat C6 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed